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21
active portfolio companies
+
2000
employees worldwide
7
AP-II Investments to Date
9
successful exits
news
Jun 01, 2026
ROADS Phase 3 Clinical Trial Data Presented at ASCO26 Show GammaTile® Provides Superior Tumor Control Leading to Patients Living Longer Without Recurrence Compared to Standard of Care in Newly Diagnosed Operable Brain Metastases
Results support GammaTile (cesium-131 collagen tile-based radiation therapy, or TBRT) as a new
standard of care for achieving optimal outcomes in this patient population
Superior efficacy achieved without increased side effects
Data presented in late-breaking abstract at the 2026 Annual Meeting of the American Society of
Clinical Oncology (ASCO26)
Apr 09, 2026
Click Therapeutics and Boehringer Ingelheim Announce Series D Investment and Funding to Advance Commercialization of CT-155- The financing combines a $50M Series D investment by Boehringer Ingelheim with additional dedicated funding to support commercialization. As part of the agreement, Boehringer is transferring responsibility for commercializing CT-155 to Click Therapeutics.
- Granted Breakthrough Device Designation by the FDA in 2024,1 the CT-155 Phase III CONVOKE study was the first and only pivotal trial to show a statistically significant reduction in experiential negative symptoms of schizophrenia as an adjunct to standard of care antipsychotic treatment.2,3
- Treatment with CT-155 demonstrated a Cohen’s D effect size of -0.36 (p value= 0.0003) reflective of a 6.8-point improvement of negative symptoms severity as measured by CAINS-MAP at 16 weeks (vs. 4.2-point in digital control arm), representing a 62% relative improvement.2
- Click Therapeutics’ expertise in digital therapeutics, experience in the mental health space, and commitment to patient-centric approaches position the company well to bring this important therapy to patients.
Apr 09, 2026
Bioness Medical Acquires the Portable Neuromodulation Stimulator (PoNS®) SystemStrategic addition expands Bioness Medical’s platform into non-invasive central neuromodulation and strengthens leadership in neurorehabilitation
Aug 07, 2025
Boehringer and Click Therapeutics’ investigational prescription digital therapeutic CT-155 meets primary endpoint in CONVOKE study for negative symptoms in schizophrenia- CT-155 showed a reduction in experiential negative symptoms as an adjunct to standard of care antipsychotic therapy from baseline to week 16, as measured by CAINS-MAP.
- CT-155 is an investigational prescription digital therapeutic being evaluated to target negative symptoms of schizophrenia in a registrational randomized clinical trial.1,2
- Often underappreciated and less recognized, negative symptoms impact more than half of people living with schizophrenia.3
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